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Inhibition of Cyclooxygenase-2 Upregulates the Nuclear Factor Erythroid 2-related Factor 2 Signaling Pathway to Mitigate Hepatocyte Ferroptosis in Chronic Liver Injury

Gasdermins can be cleaved and activated by a diverse array of other proteases in addition to caspase-1, including hematopoietic cell proteases (for example, granzymes, neutrophil elastase and cathepsin G) 17 and bacterial virulence factors (for example, SpeB) 18

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10.1016/j.pupt.2004.06.002 93 JuniorW