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Data are expressed as mean ± standard deviation Abbreviations: BMI body mass index, FBS fasting blood sugar, IRI immunoreactive insulin, HBA1c hemoglobin A1c, HDL cholesterol high density lipoprotein cholesterol, LDL cholesterol low density lipoprotein cholesterol, NEFA non-esterified fatty acid, AST asparate aminotransferase, ALT alanine aminotransferase, GGT γ-glutamyl transpeptidase, CAP controlled attenuation parameter, LSM liver stiffness measurement The characteristics of ALT responders and non-responders before and after glutathione treatment are shown in Table 3

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Other studies have demonstrated that treatment with H1R and H4R antagonists reduces the production of pro-inflammatory cytokine IL-6 [65,66]