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In addition, a modulator of PPARγ, apigenin, was also revealed to attenuate NAFLD by Nrf2-associated regulation of oxidative stress and hepatocyte lipid metabolism (Feng et al., 2017)

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In these rats, levels of LPO in the spleen tissues were increased, whereas the activities of SOD and CAT were significantly decreased compared with those in the control group (Ibrahim et al., 2022)