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Females showed greater modulation of nutrient-sensing pathways, while males exhibited stronger suppression of oxidative stress-related programs, consistent with known sex-dependent differences in metabolic and neuroimmune regulation in aging [26-27]
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Figure 1 Although previous studies have demonstrated that GLP-1 has positive effects on attenuating neuropathology, its function and specific actions in CNS diseases have not been reviewed comprehensively
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