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GSH metabolism promotes the proliferation of HG cells Stem cells change metabolism during homeostasis and proliferation [37], and glutamine metabolism is constantly shifted among HFSCs during their exit from their bulge niche to produce outer root sheaths during anagen progression, as well as the return of a subset of outer root sheath progeny to the bulge niche to restore the stem cell state to adapt to and regain reversibility of the HFSC fate during catagen [5]

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Early symptoms may include: The timing depends on dosage, frequency, and individual response