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Mechanistically, Saracatinib inhibits TGF-β-induced Smad3 phosphorylation, thereby suppressing key fibrotic markers—such as α-SMA, type I collagen, and plasminogen activator inhibitor-1 (PAI-1)—in human lung fibroblasts, while reversing EMT-related pathways (Hu et al., 2014
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Studies indicate that acupuncture may alleviate BMS symptoms by stimulating specific acupoints, such as SI1 (Shaoze), TE1 (Guanchong), LI4 (Hegu), TW21 (Ermen), ST5 (Daying), ST6 (Jiache) and CV24 (Chengjiang) [49, 50, 51, 52, 53]
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