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have shown that TLR4–TIR-domain-containing adapter-inducing IFN-β (TRIF)–TNF receptor-associated factor 6 signaling is a key pathway controlling the severity of acid-induced ALI 80

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The findings of the present study demonstrate that a high-fat, high-sucrose diet, which causes chronic hepatosteatosis similar to human fatty liver, reduces hepatic NAD + levels and consequently diminishes mitochondrial content, function, and adenosine triphosphate production