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Some of these mechanisms focus on producing reactive oxygen species, glutathione depletion, plasmid curing inhibition, efflux pump inhibition, and resistance enzyme inhibition 46,47
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extract (CSE) reduced A β accumulation in the hippocampus of 5XFAD mice, increased A β -degrading enzymes (IDE, NEP), activated ApoE clearance proteins, improved synaptic proteins (PSD-95, SNAP-25), reduced neuroinflammation, and promoted astrocyte activation
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