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Combined, such studies led to the hypothesis that ACh plays an important role in the development of the intricate retinal network, perhaps by contributing to the initiation and propagation of retinal waves, while also contributing to the growth and connectivity of retinal cells

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In line, hyperuricemia was associated with inflammation, oxidative stress, renal hyperfiltration, proteinuria, and chronic kidney disease (Chaudhary, Malhotra, Sowers, & Aroor, 2013)