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Arrowhead has granted Madrigal an exclusive global license to ARO-PNPLA3, a RNAi therapeutic designed to reduce liver expression of PNPLA3 as a potential treatment of metabolic dysfunction-associated steatohepatitis. As per the deal
In vascular-related ED, increased oxidative stress results in reduced endothelial function due to decreased NO availability and heightened vasoconstriction
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