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The FDA's Pharmacy Compounding Advisory Committee is scheduled to meet Thursday and Friday to review some of the controversial, popular peptide injections and discuss whether compounding pharmacies should be able to dispense
Preclinical: In a comparative study assessing the protective benefits of IN-EPO versus invasive intracerebroventricular (ICV) administration in an Aβ 25–35 non-transgenic mouse model of AD, ICV-EPO at a dose of 125–500 µg/kg, IN-EPO at a much lower dose of 62–250 µg/kg, and low sialic form termed ‘Neuro-EPO’ (also intranasal) significantly prevented Aβ-induced learning deficits, hippocampal neurodegeneration, and reduced levels of neuroinflammatory markers tumor necrosis factor (TNF) and interleukin-1β (IL-1β) [30]
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doi: 10.1016/j.clinbiochem.2007.04.007 [DOI] [PubMed] [Google Scholar] 4.Scalabrino G
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