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178 For example, hybrid nanodrugs (HREDs) derived from citrus extracellular vesicles reduce ATP levels and suppress efflux activity, demonstrating potent antitumor effects in drug-resistant ovarian cancer models
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Nle 1 -AngIV, an often-employed AT 4 receptor agonist with demonstrated procognitive activity (Benoist et al., 2011), along with its metabolically stabilized and orally active derivative, N -hexanoic-tyrosine-isoleucine-(6) aminohexanoic amide (dihexa) (McCoy et al., 2013), were utilized to probe this question