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The domain encompasses both overload and underloading, including boom-and-bust pacing patterns, post-exertional worsening, deconditioning, and poor tolerance of generic exercise prescriptions (26, 27, 31)
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H 2 S can be produced, for example, by 3-mercaptopyruvate sulfurtransferase (3-MST), which is also one of the H 2 S-producing enzymes ( 2 S through 3-MST also requires cysteine aminotransferase (CAT), which catalyzes the reaction of cysteine with keto acids to form 3-mercaptopyruvate and the corresponding amino acid