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Connexin 43 hemichannels are permeable to ATP
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for such mechanism full activation (opening) of SV/TPC1 channels, which is only observed at rather high cytosolic Ca 2+ , is not necessary so that the channel protein may operate in a non-canonical ion flux-independent way (Pottosin & Dobrovinskaya, Reference Pottosin and Dobrovinskaya2022)
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