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As the healing process progresses to the later stage of remodeling, the main components of ECM change, and type III collagen is gradually replaced by type I collagen, which is accompanied by the hardening and reinforcement of ECM, and ultimately leads to the formation of mature scars ( In the study conducted by Razieh Nazari-Vanani and colleagues, a stretchable TENG was introduced as a stimulant to accelerate cellular proliferation and migration ( In vitro results indicated that the TENG patch enhanced fibroblast migration by 10% and 20% at 12 and 24 h, respectively, compared to the control group
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