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10.1016/j.freeradbiomed.2008.09.027 39 ClulowJ

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Targeted delivery of IGF-I to spinal cord motor neurons via intramuscular injection of IGF-I, fused to non-toxic tetanus toxin fragment-C (TTC), promoted maintenance of muscle fiber innervation and prevented neuromuscular junction atrophy and fragmentation in aged muscle fibers[32]