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In murine models, the administration of Astragalus was observed to reduce bronchial inflammation, as well as to prevent bronchospasm and bronchial remodeling [69,70,71]

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Consistent with these reports, previous lineage tracing of Nestin + MSCs in vivo revealed a relatively quiescent state in adult mice as minimal GFP positive cells could be identified one month after induction, whereas abundant GFP expression was detected 8 months after induction (27)