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In agreement with these data, we have observed that UDCA alone improves the intestinal Ca 2+ absorption by increasing the amount of Ca 2+ transporters involved in the transcellular Ca 2+ pathway via activation of the VDR gene and protein expression

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The PHD domain of MEKK1 acts as an E3 ubiquitin ligase and mediates ubiquitination and degradation of ERK1/2