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This perspective compiles the most recent strategies for enhancing PDC treatment efficacy, highlights key advancements in PDC, and provides insights on future directions for the development of novel PDCs

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Notably, patients with minimal/mild endometriosis-associated infertility achieve lower success rates with stimulation and IUI compared to women with unexplained infertility, but ablation of minimal/mild endometriosis normalizes clinical pregnancy rates per cycle and cumulative birth rates, indicating that endometriosis exerts a reversible detrimental effect on fertility ( In vitro fertilization (IVF), including intracytoplasmic sperm injection (ICSI), is recommended for moderate-to-severe endometriosis, particularly in cases with ovarian endometriomas larger than 3 cm and/or deep infiltrating endometriosis, even when tubal patency and semen parameters are normal