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This older group of patients should be closely monitored during treatment with valproic acid for the development of acute liver injury with regular clinical assessments and serum liver test monitoring
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2.1.4 Modulation of cancer-related signalling pathways Emerging pre-clinical evidence suggests that VCO and LA influence cancer-related signaling pathways, affecting aspects such as cell cycle transition, apoptosis, growth, oxidative stress response, immune activation, cyclin-dependent kinase activity, EGFR signaling pathways, etc.,
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