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Paul Talalay and researchers at Johns Hopkins University linked these findings (Prochaska et al., 1992) and identified sulforaphane, isolated from broccoli, as a potent inducer of phase II detoxification enzymes including glutathione-S-transferase (GST) and NAD(P)H oxidoreductase 1 (NQO1) (Zhang et al., 1992)

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Fan S, Tian T, Chen W, Lv X, Lei X, Zhang H, et al