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A comprehensive search of the literature was carried out through the PubMed electronic database from inception to 31 December 2023 using the following search terms “vitiligo” AND “JAK inhibitors”, “vitiligo” AND “prostaglandin”, “vitiligo” AND “afamelanotide”, “vitiligo” AND “antioxidants”, “vitiligo” AND “vitamin D3”, “ vitiligo” AND “statins”, “vitiligo” AND “TNF-alpha”, “vitiligo” AND “interleukin”, “vitiligo” AND “light therapy”