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As part of a broader family of naturally occurring and synthetic copper-peptide complexes, AHK-Cu has attracted research interest because of the important role copper ions play in numerous biological processes and enzyme systems

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Exposure to ROS can also bring modulation the expression of different transcription factors such as nuclear factor kappa B (NF-kB), and activator protein 1 (AP-1), involved in cancer stem cell maintenance, metastasis, and proliferation