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B-Cell Targeting Therapies Beyond Depleting Antibodies: Tyrosine Kinase Inhibitors Selective inhibitors of tyrosine kinase (TK) or Bruton’s tyrosine kinase (BTK), key components of B-cell receptor signaling that regulates B cell proliferation, survival, adhesion and migration as well as Toll-like receptor signaling 1 are being studied in several clinical trials
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