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Stack #5: Semaglutide + AOD-9604 (“Appetite control + fat mobilization”) Why it’s popular: People want the GLP-1 appetite effect plus something that “targets fat.” What semaglutide’s evidence actually looks like Semaglutide 2.4 mg once weekly has strong RCT evidence for substantial weight loss when paired with lifestyle intervention (e.g., STEP trials)
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Additionally, we established practices for the removal of such measures, such as establishing the topped-out measure lifecycle, to continue to drive quality improvement in areas where such improvement is possible and necessary
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