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it is a crystal deposition disease in which crystals of monosodium urate form in joints and other tissues
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Peptide-mediated PrfA inhibition by competitive occupancy of the tunnel binding site for GSH 25,29 , itself a tripeptide, could be attributed to rapid, transient protein-peptide interactions with relatively weak affinity, like those that dynamically regulate cellular processes via Short Linear Motifs (SLiMs) 39
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