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However, substitution of this histidine with an aspartate residue did not alter the mutant β-synuclein’s behaviour as compared to the wild type with respect to this pH dependent conformational change ( 2.5 Effect of phosphorylation α-synuclein recovered from Lewy bodies of patients affected with sporadic Parkinson’s disease and LBD as well as from glial cytoplasmic inclusion bodies in oligodendrocytes of patients affected with Multiple System Atrophy has been found to be heavily phosphorylated in the 129th serine residue of the C terminal domain (Pronin et al., 2000), the casein kinase II (Sano et al., 2021), polo-like kinases ( 2.6 Effect of glycation The process of attachment of sugar molecules on lysine and arginine residues of proteins via formation of Schiff’s base is referred to as glycation

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Multiple studies have found that depriving herpes simplex virus of arginine can halt its replication