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As semaglutide and tirzepatide seek to expand their approved indications, e.g., potentially adding heart failure, chronic kidney disease or MASH, following several successful phase 3 trial readouts in 2023 and 2024, more pathways open up to Medicare reimbursement of AOMs within existing rules
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This dual approach to sustainable and lifelong health is in line with contemporary views on human physiology and health (173–175), which requires a systemic perspective that integrates multimodal data from various entities to create a network functioning in health and disease and to explore its dynamic responses to disturbances (176)
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