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Measurements and expressions of pain in itself are also very hard to quantify which makes it a difficult subject to research

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Two randomized, double-blind, placebo-controlled trials of ataluren 156,157 , an orally bioavailable small molecule that induces ribosomal read-through of nonsense mutations, failed to achieve the 48 weeks primary endpoint of improved distance walked in the 6-minute walk test (SMWT) compared with patients who received placebo treatment

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