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Methods: Fifty-eight patients with paraclinoid aneurysms on one side and two patients with paraclinoid aneurysms on both sides were enrolled

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In the 536 bp site of the proximal promoter of GGT, a binding site exists between p50, TNF-α and Sp1, regulated by the activation of the NF-κB signaling pathway, thereby promoting expression of GGT and inducing inflammatory response (Fig