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The commenters stated that to be consistent with other modifier -51 exempt codes, the multiple procedure indicator (MPPR) for these codes should be updated to “0” while the diagnostic imaging family indicator should be updated to “99”

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10 µg/kg is most commonly cited Colitis model (rat): 10 µg/kg IP daily or oral equivalent Cardiac ischaemia-reperfusion (rat): 10 µg/kg IP single or repeated dosing For dose-ranging studies, a typical design uses 1 µg/kg, 10 µg/kg and 100 µg/kg arms to capture the central dose range