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[40] Anabolic fates of pyruvate Under anabolic conditions, the carbon skeleton of pyruvate can follow fates other than complete oxidation to CO 2 or reduction to lactate

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An interesting approach involves using a cathepsin-cleavable valine-citrulline (Val-Cit) linker in a macromolecular prodrug platform for pulmonary intracellular infections, providing controlled drug release and enhanced antibacterial efficacy (Fig

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