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the specific elongation factor EFSec, SECIS binding protein 2, ribosomal protein L30, SECp43, and possibly other yet unidentified factors [30]

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This metabolic substrate-specific regulatory mechanism suggests that cells can dynamically adjust the ferroptosis threshold by reprogramming the carbon source utilization pattern (such as switching from glucose metabolism to glutamine metabolism), providing a theoretical basis for intervening in ferroptosis by targeting energy metabolism (41)