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Effective October 1, 2021, CMS retired it and created three specific replacements: M54.50 : Low back pain, unspecified, for documentation that says only "low back pain" or "lumbago" M54.51 : Vertebrogenic low back pain, for imaging-confirmed vertebral endplate pathology M54.59 : Other low back pain, for characterized pain types (mechanical, muscular) that don't meet vertebrogenic criteria Using M54.5 on claims submitted today will result in automatic rejection