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Even though under normal circumstances dietary inorganic sulfate contributes very little to our sulfate pool, the exogenous administration of small amounts of sulfate in selected forms of delivery may be useful, since contrary to what is still a common belief sulfate can be absorbed form the GI tract [41,51]

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This relation was explicitly applied to the estimation of acid dissociation constants by Waldron in the 1950s57 and by Kiso et al in the 1960s58 using a paper strip as a supporting medium