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Fruit ripening-associated leucylaminopeptidase with cysteinylglycine dipeptidase activity from durian suggests its involvement in glutathione recycling | BMC Plant Biology | Springer Nature Link

Additionally, peroxynitrite oxidizes tetrahydrobiopterin, an essential cofactor for eNOS, rendering it biologically inactive and unable to catalyze endothelial NO synthesis [15]

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In specific abnormal cardiac conditions, like arrhythmias, berberine may serve as a beneficial adjunctive therapy, with the efficacy of amiodarone, but no side effect [55]