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A correlation was found between self-perceived fatigue after a psychomotor vigilance task and high rCBF in the left medial frontal and anterior cingulate gyri

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Mechanistically, Arctigenin downregulated CPT1-mediated FAO, which further inhibited nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome assemblies in macrophages (Qiao et al., 2020)

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