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Neurological autoimmune diseases (NAD) NAD are characterized by inappropriate immune responses, including the presence of autoantibodies targeting self-antigens in the central nervous system and peripheral nervous system, leading to abnormal immune reactions and the occurrence of NAD

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Then, we explore the molecular and functional changes in the BBB that occur during normal ageing, neurodegeneration and acute brain injuries, and how prolonged BBB impairment affects transport mechanisms and disease progression