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Such affinity depends on proximity between the catalytic Cys 47 -sulfenate of Prx6 and activated GSH (thiolate) bound to the GSTP1-1 allelic variant, regulating the activation of the sulfenate through S-glutathionylation [17]

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Cells treated with non-targeting siRNA (“c”) or siRNA against QRICH were treated for 16 h and subjected to WB (up) and their supernatant to LIF ELISA (bottom, n = 3)

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