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Some groups have designed biocompatible scaffolds that may incorporate features supportive of the NP cell phenotype, such as the inclusion of native extracellular matrix components, such as hyaluronan, proteoglycans, or collagens (102, 103) (104)

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We are maybe in an unusual position whereby while we may not have the direct clinical trial data to definitively say they do or do not work, we have been undertaking full (minimum 70 marker) detailed venous screening (and body composition analysis) with people using since June (around 150 people) so we have that internal evidence