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On the other hand, peroxidases-driven reactions are using low relative molecular mass antioxidants, GSH and Asc as electron donors, so removal of H 2 O 2 using this pathway may be a very energy-consuming reaction for cell since it utilizes important molecules from the cell environment: two GSH molecules are consumed for removal of one H 2 O 2 molecule (Kohen and Nyska, 2002)
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Recombinant CARDS Tx induces expression of Th-2 cytokines IL-4 and IL-13, as well as Th-2 chemokines CCL17 and CCL22, thereby triggering a mixed cellular inflammatory response characterized by the accumulation of eosinophils, T cells, and B cells (60)