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A Comprehensive Approach to Parkinson's Disease: Addressing Its Molecular, Clinical, and Therapeutic Aspects
De novo lipogenesis is the process in which hepatocytes convert excess carbohydrates, especially fructose, into fatty acids [2], it is strictly regulated by nuclear receptor and cytoplasmic transcription factors including the liver X receptor (intervening in hepatic fatty acid synthesis), the farnesoid X receptor (interfering in VLDL assembly) and the peroxisome proliferator-activated receptors [PPARs] family [7]
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47,48 These synthetic protein preparations exhibit partial or complete amino acid sequence homology with endogenous GLP-1, rendering them resistant to degradation which resulting in a prolonged half-life and heightened biological activity
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