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Glutathione and redox signaling in substance abuse - ScienceDirect

[DOI] [PMC free article] [PubMed] [Google Scholar] 463.Shiraiwa K, et al

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In septic mice, intravenous (i.v.) administration of Cur@Ce/OCS demonstrated multimodal therapeutic efficacy by synergistically achieving a 97 % reduction in bacterial load, mitigating the systemic cytokine storm evidenced by significant reductions in IL-6 (81.5 %), IL-1β (45.9 %), and TNF-α (66.7 %), and enhancing the survival rate to 85 % versus 20 % in the control group