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α-Synuclein (α-Syn) binds Cu 2+ with high affinity via its N-terminal amine, the side chain of Asp2, and the imidazole group of His50, inducing conformational changes that modulate copper redox activity, reduce oxidative stress, and promote membrane recycling and SNARE-complex membrane fusion (172)

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Aim to have your glutathione level in the upper end of the spectrum

or other open areas of skin.