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Histopathological analyses have demonstrated that the chronic constriction injury (CCI) model is typified by nerve fiber demyelination, axonal degeneration, and a decrease in Aβ fibers (45, 47), while the majority of C-fibers remain relatively intact, and this specific injury pattern is closely associated with mechanical and thermal nociceptive sensitization in neuropathic pain (46)
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The impact of KD on abnormal brain glucose metabolism The brain is the most energy-intensive organ in the body