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FIGURE 3 To further confirm the hypothesis of a regulation of CBS activity by the Akt/GSK3β and/or NF-κB pathways, we assessed the impact of inhibitors of these pathway (9-methylstreptimidone, 8α-hydroxy verrucarin A, chrysomycin and daunorubicin) on the mRNA levels of CBS , CSE and NAD(P)H quinone oxidoreductase 1 ( NQO1 ), three genes known to be regulated by these pathways (Wang et al., 2014
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