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Iron plays a crucial role in biological interactions, including the virulence of the Aspergillus fumigatus, suggesting that fungal iron homeostasis is a promising target for improvement of antifungal treatment and diagnosis of fungal infections (Misslinger et al

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In addition, a decrease in copper transport could also lead to a decrease in diamine oxidase (DAO) activity [348, 349], altering histamine metabolism and generating the appearance of symptoms caused by its accumulation [350]