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Antioxidants 12 , 1477 (2023)

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Our results show that the metabolite of glucarate salts, GA, mitigate liver toxicity by: (1) reducing ROS production in hepatocytes, (2) lowering hepatic apoptosis, (3) reducing β-glucuronidase in hepatocytes, and (4) reducing glucuronide deconjugate levels in the bile