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Meanwhile, POR and CYB5R1 can also transfer electrons from NAD(P)H to oxygen to generate hydrogen peroxide, which subsequently generates reactive hydroxyl radicals through the Fenton reaction and further promotes the production of LPO, destroying the integrity of the cell membrane [48]

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Binding of FcγR-GST and biotinylated human IgG1 brings the acceptor and donor beads into close proximity