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IGF-1 has complex regulatory functions in adult human hematopoietic progenitor cells and can stimulate the proliferation of both myeloid and erythroid progenitors through its interactions with IGF-1 receptor (IGF-1R) 17,18

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Necrotizing fasciitis can start as a cut on the leg and end in amputation and, though rare, it has a high mortality rate, according to the Mayo Clinic